abstract |
Disclosed is the use of (i) a bisthiazolium salt of formula (VI) or a precursor thereof, wherein the variables are as defined in the specification, and (ii) artemisinin or a derivative thereof, chosen from artesunate, artemether, arteether, hydroartemisinin or dihydroartemisinin in the manufacture of a combination for the treatment and/or prevention of severe malaria. |