http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-586642-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e8432ebff5a06ee8a6ffec8cc7611fbd |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2009-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d629f311baca323ccbb684e42d483b91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab3c8312907f2be84689bb4fad794fed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65cc2844ef0da3957ae1729311bea84d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cba0b6ef718f413586bbbfc016cc77c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecb497047eee51abef8f821d0b310895 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2572f863fab7542c78b11d0cf87fa0b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_324c43121437f84376d56033defb1bf5 |
| publicationDate | 2012-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-586642-A |
| titleOfInvention | Novel pyrazolo [3, 4 -d] pyrimidine derivatives as anti -cancer agents |
| abstract | Disclosed are substituted pyrazolo pyrimidine compounds of formula I, salts thereof, and methods for their preparation. Specific examples of compounds of formula I include: (4-methoxy-benzyl-[1-(3-ethynyl-phenyl)-1H-pyrazolo [3,4-d] pyrimidine-4yl)-amine, [1-(3-trimethylsilanyl ethynyl-phenyl)-1H-pyrazolo[3,4-d]pyrimidine-4yl)-(3,4,5-trimethoxybenzyl)-amine, and [4-(3-morpholin-4-yl-propoxy)-benzyl]-[1-(3-iodo-phenyl)-1H-pyrazolo[3,4-d]pyrimidine-4yl)-amine. Specifically disclosed is a synthetic method for N-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)-1-(3,5-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine. Also disclosed is the use of a compound of formula I for treating lung cancer, squamous cell cancer, bladder cancer, gastric cancer, pancreatic cancer, breast cancer, head cancer, neck cancer, esophageal cancer, brain cancer, gynecological cancer, prostate cancer, kidney cancer, leukemia, lymphoma or thyroid cancer. |
| priorityDate | 2008-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 585.