http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-584842-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bcff13f8573db698307f919e6385d5c4 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D243-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-18 |
| filingDate | 2008-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe940c5280104f36044bca78a5887f8e |
| publicationDate | 2012-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-584842-A |
| titleOfInvention | Benzodiazepinone compounds useful in the treatment of skin conditions, in particular, psoriasis |
| abstract | Disclosed are benzodiazepinone compounds of formula I, R and S enantiomers, salts and esters thereof, and methods for their preparation. Specific examples of compounds of formula I include (Z)-7-chloro-5-(4-hydroxyphenyl)-3-(2-methylbenzyl)-1H-benzo[e][1,4]diazepin-2(3H)-one, (Z)-7-chloro-3-(3,5-diisopropylbenzyl)-5-(4-hydroxyphenyl)-1H-benzo[e][1,4]diazepin-2(3H)-one, (Z)-7-chloro-3-(2,5-diethylbenzyl)-5-(4-hydroxyphenyl)-1-methyl-1H-benzo[e][1,4]diazepin-2(3H)-one, and (Z)-7-chloro-3-(2,6-diethylbenzyl)-5-(4-fluoropheny)-1H-benzo[e][1,4]diazepin-2(3H)-one. Compounds of formula I may be included in pharmaceutical compositions further comprising other agents such as vitamin D or steroids. The compounds are useful for treating atopic dermatitis, rosacea, psoriasis, and skin conditions associated with epidermal hyperplasia. |
| priorityDate | 2007-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 376.