| abstract |
Disclosed herein are substituted N-phenyl-bipyrrolidine ureas of formula (I), wherein the substituents are as defined within the specification, methods for their preparation, compositions comprising said compounds and uses thereof. Said compounds are modulators of H3 receptors and therefore are useful in the treatment and/or prevention of diseases modulated by H3 receptors such as diseases associated with the central nervous system, sleep related disorder, dementia, Alzheimer's disease, multiple sclerosis, cognitive disorder, attention deficit hyperactivity disorder and depression. |