| abstract |
Disclosed are cyclopentane compounds represented by general formula (I) such as: 5-(3-((1R,2R,3R,5R)-5-chloro-2-(3,5-dichlorostyryl)-3-hydroxycyclopentyl)prop-1-enyl)thiophene-2-carboxylic acid; 5-(3-((1R,2R,3R,5R)-5-chloro-2-(3-chloro-5-(hydroxymethyl)styryl)-3-hydroxycyclopentyl)propyl)-thiophene-2-carboxylic acid; and 5-(3-((1R,2R,3R,5R)-5-chloro-2-((E)-2-(5-chloropyridin-3-yl)vinyl)-3-hydroxycyclopentyl)propyl)-thiophene-2-carboxylic acid; The compounds are used to treat intraocular pressure. |