| abstract |
The disclosure relates to pyrazolopyrrolidine compounds of formula (I) wherein A, Y, R1, R1a, R2, and R2a are as described in the specification. These compounds of formula (I) are inhibitors of gamma secretase and are useful in treating and/or preventing cognitive disorders, such as Alzheimer's disease. The disclosure also relates to pharmaceutical compositions comprising compounds of formula (I), to methods of preparing compounds of formula (I), and to methods of treating cognitive disorders, such as Alzheimer's disease. |