http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-581767-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2cf7f3f36d20185ce15a2d1f04d5fdc1 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-284 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2853 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-167 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-28 |
| filingDate | 2007-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_243c989fcf70a74197bbd74fab4b1569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b97fa2635a5ac3ca64c56081c389304 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d67f4719b904ca56d313c76196139fb |
| publicationDate | 2012-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-581767-A |
| titleOfInvention | Formulations of nonopioid and confined opioid analgesics |
| abstract | Disclosed is a pharmaceutical composition consisting of a monolithic core layer and a nonporous outer non-core layer, (A) wherein the core layer comprises a mixture of: (a) at least one opioid such as hydrocodone and (b) at least one (meth)acrylate polymer and at least one cellulose derivative; (B) wherein the non-core layer consists of a non-opioid analgesic, a polyvinyl alcohol-polyethylene glycol-graft polymer, and colloidal silica; (C) wherein the composition is adapted so as to be useful for oral administration to a human 3,2, or 1 times daily; (D) wherein the core layer is manufactured by melt-extrusion followed by direct shaping of the drug-containing melt; (E) wherein the active ingredients in the core layer are in a solid solution formed by the polymers of (b); and (F) wherein the non-core layer is applied to the core layer as an aqueous solution or suspension with a total solid content of at least 20percent by weight and an active ingredient content of at least 50 percent. |
| priorityDate | 2007-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 282.