Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d821543cc4e5f7c564c1e9c9a0573159 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10343 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 |
filingDate |
2008-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9be6c9508112aed06df3bfbd7d4de868 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_517fb3edb5407bae0772c58865a44d7c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f28104a3eab834f414b39d801f48b957 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_648946665c1f07e984010121a93d3fae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a53d1d37bc0706e00a540aed1ec0972 |
publicationDate |
2012-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
NZ-581511-A |
titleOfInvention |
Nucleic acid construct comprising a conditionally replicating adenovirus transciptionally linked to a cis regulatory element such as a PPE-1 promoter and uses thereof in the regulation of angiogenesis |
abstract |
Disclosed is the use of a nucleic acid construct comprising an isolated polynucleotide which comprises a conditionally replicating adenovirus-5 genome transcriptionally linked to a pre-proendothelin-1 promoter for the manufacture of a medicament for treating a disease or condition associated with excessive neo-vascularization in a subject in need thereof, wherein said promoter selectively directs replication of said adenovirus in angiogenic endothelial cells, and wherein said nucleic acid construct comprises said pre-proendothelin-l promoter and a consecutive adenoviral E1 region. |
priorityDate |
2007-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |