| abstract |
Disclosed is a compound of formula (I) where the substituents are as disclosed in the description. Examples of compounds of formula (I) include N-(1-( 4-(methylamino)cyclobexyl)-1,2,3,4-tetrabydroquinolin-6-yl)thiophene-2-carboximidamide. Also disclosed is a pharmaceutical composition comprising a compound of formula (I) and the use of a compound of formula (I) in the manufacture of a medicament for the treatment of conditions caused by nitric oxide synthase (NOS). Examples of conditions are Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis (ALS), Huntington's disease, multiple sclerosis, neurotoxicity, or head trauma. |