abstract |
Disclosed is an anti-VEGF antagonist comprising an amino acid sequence that is identical to the amino acid sequence of DOM 15-26-593 or differs from the amino acid sequence of DOM 15-26-593 at no more than 10 amino acid positions and has a CDR2 sequence that is at least 50% identical to the CDR2 sequence of DOM 15-26-593, wherein the amino acid sequence of DOM 15-26-593 is as set out in Figure 5. |