Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7134c9fb0602d6a09d1bf63203ce43a6 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L5-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4523 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4453 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-381 |
filingDate |
2009-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4bbb44b7b98a25d98efb3a646760266 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddc4d3266e545fcb3fceb8e010c76a13 |
publicationDate |
2010-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
NZ-578451-A |
titleOfInvention |
Inclusion complex of raloxifene hydrochloride and beta-cyclodextrin. |
abstract |
Disclosed is an inclusion complex of raloxifene hydrochloride and b-cyclodextrin (wherein the inclusion complex has the following peaks at diffraction degrees (2-theta) in the X-ray powder diffraction spectrum ±0.2: 10.6, 12.4, 14.4, 15.3, 19.0 and 19.5). Also disclosed is a process for obtaining the inclusion complex of raloxifene hydrochloride with b-cyclodextrin as defined above which comprises the following steps: A) dissolving raloxifene hydrochloride in an aqueous solution; B) heating the mass to a temperature ranging from 50 to 80°C; C) adding b-cyclodextrin; D) separating the raloxifene hydrochloride-b-cyclodextrin complex by precipitation and filtration. Further disclosed is the use of an inclusion complex as defined above for manufacturing a medicament for the treatment of osteoporosis or postmenopausal osteoporosis. |
priorityDate |
2009-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |