http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-578451-A

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filingDate 2009-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4bbb44b7b98a25d98efb3a646760266
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publicationDate 2010-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber NZ-578451-A
titleOfInvention Inclusion complex of raloxifene hydrochloride and beta-cyclodextrin.
abstract Disclosed is an inclusion complex of raloxifene hydrochloride and b-cyclodextrin (wherein the inclusion complex has the following peaks at diffraction degrees (2-theta) in the X-ray powder diffraction spectrum ±0.2: 10.6, 12.4, 14.4, 15.3, 19.0 and 19.5). Also disclosed is a process for obtaining the inclusion complex of raloxifene hydrochloride with b-cyclodextrin as defined above which comprises the following steps: A) dissolving raloxifene hydrochloride in an aqueous solution; B) heating the mass to a temperature ranging from 50 to 80°C; C) adding b-cyclodextrin; D) separating the raloxifene hydrochloride-b-cyclodextrin complex by precipitation and filtration. Further disclosed is the use of an inclusion complex as defined above for manufacturing a medicament for the treatment of osteoporosis or postmenopausal osteoporosis.
priorityDate 2009-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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