| abstract |
Provided is the use of ActRII polypeptide, which is an activin-binding inhibitor of activin, in the manufacture of a medicament to treat anemia. Specific amino acid sequences for soluble forms of the polypeptide are provided, as well as variants of the sequences. The polypeptides may be used in fusion proteins with peptides enhancing stability, half-life and other useful properties as a medicament. |