| abstract |
Disclosed are compounds of formula (I) which have a 3,3a,4,5-tetrahydro-2H-benzo[g]indazole core structure and the substituents are as disclosed in the description. Also disclosed is a pharmaceutical composistion containing a compound of formula (I) and the use of a compound of formula (I) in the preparation of a medicament for treating cardiovascular conditions, renal conditions, liver conditions, vascular conditions, inflammatory conditions, pain, retinopathy, neuropathy, insulinopathy, edema, endothelial dysfunction or baroreceptor dysfunction. |