| abstract |
Disclosed are 2-alkoxy-1-arylsulphonyl and 2-alkoxy-1-heteroarylsulphonyl piperidine derivatives as represented by the general formula (I), wherein n represents 0, 1, 2 or 3; m represents 1 or 2; R1 represents aryl or heteroaryl; and the remaining substituents are as defined herein. Further disclosed is a medicament composition comprising a compound as defined above for the treatment of migraine, diabetes, respiratory diseases, inflammatory intestinal diseases, neurological diseases, inflammations of the skin, rheumatic diseases, septic shock, reperfusion syndrome and obesity, and as an angiogenesis inhibitor. |