| abstract |
Disclosed a composition for use in the treatment of atherosclerosis or diseases associated with atherosclerosis, heart disease, stroke, peripheral artery diseases, angina, restenosis and atheroma or a vascular disease selected from anyone of atherosclerosis, heart disease, stroke or peripheral artery disease or for the treatment or prevention of cancer selected from skin cancer, breast cancer, colon cancer or prostate cancer, which composition comprises an inhibitor of PPAR delta activity wherein said inhibitor of PPAR delta activity is a nucleic acid-based inhibitor of PPAR delta activity in a cell being a PPAR delta-selective antisense molecule or a PPAR delta-selective ribozyme. (62) Divided Out of 556520 |