| abstract |
Disclosed is an isolated Replikin Scaffold peptide consisting essentially of the sequence KKNSTYPTIKRSYNNTNQEDLLV[X]WGIHH (SEQ ID NO: 1) wherein the residue [X] is an isoleucine, a glycine, an alanine, a valine, a proline, a phenylalanine, a tryptophan, a serine, a threonine, a tyrosine, a cysteine, an asparagine, or a glutamine residue. Further disclosed is an isolated Replikin peptide comprising the amino acid sequence KKX1X2X3YPTIKX4X5X6NNTNX7EDLLVX8WGIX9H (SEQ ID NO: 349), wherein X1 is N or G; X2 is N or S; X3 is A or T; X4 is R or K; X5 is S or T; X6 is any amino acid residue; X7 is any amino acid residue; X8 is isoleucine, glycine, alanine, valine, proline, phenylalanine, tryptophan, serine, threonine, tyrosine, cysteine, asparagine or glutamine; and X9 is H or Q. |