| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c72f10d1cc69fad956829eac6e448ac8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate |
2007-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20b856102395b16afe7fff4f79bd540c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d208f9c1f189da00458bc54b788dc0be
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2eb92b5fc6363e19a11454c9ca502ef3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_753c34b394d0c10db0efe66c28c0d1e6 |
| publicationDate |
2012-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
NZ-569697-A |
| titleOfInvention |
Method of treatment, prophylaxis and diagnosis of pathologies of the bone by the modulation of GPC3 |
| abstract |
Disclosed is the use of an agent which modulates expression of a gene or the activity of a product encoded by a human GPC3 gene or a mammalian homolog thereof, and wherein the agent is selected from the Jist consisting of (i) a nucleic acid molecule encoding GPC3; (ii) an antisense DNA or RNA molecule to a nucleic acid molecule enCoding GPC3; (iii) a hairpin RNA or siRNA molecule to a nucleic acid molecule encoding GPC3; (iv) GPC3 protein; and (v) an antibody specific for GPC3 protein, in the manufacture of a medicament for the treatment of a suture-based cranial disorder or bone injury selected from the list consisting of a fracture, greenstick and bone chip in a subject. Further disclosed is the use of an agent as defined above in the manufacture of a medicament for treating a subject to improve bone growth or inhibit bone growth in said subject. |
| priorityDate |
2006-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |