| abstract |
Disclosed are immunogenic compositions of Streptococcus pneumoniae that comprise 10 or more capsular saccharides from different carrier proteins. The composition comprises the serotypes 1, 4, 5, 6B, 7F, 9V, 14, 18C, 19F and 23F conjugates but does not comprise capsular saccharide from serotype 19A. The serotype 19F capsular saccharide is conjugated to the diphtheria toxoid (DT). The composition is used for the treatment and prevention of disease caused by S. pneumoniae infection by serotype 19A strains. |