| abstract |
Disclosed is a compound of formula I or a pharmaceutically acceptable salt, or an optical isomer thereof, wherein the substituents are disclosed within the specification. Also disclosed is the use of a compound of formula I in the manufacture of a medicament, for treating a condition in a mammal, the treatment of which is effected or facilitated by Kv1.5 inhibition such as cardiac arrhythmia or a thromboembolic event. |