| abstract |
Disclosed is a salt of a compound of Formula I wherein: A is a saturated hydrocarbon chain, forming a five- membered ring; T is -C(O)OH; G1 is -(CR1R2)n-; n is 0 or 1; X1, X2, and X3 are hydrogen; G2 is a saturated monocyclic heterocycloalkyl linker, G3 is selected from the group consisting of a bond and -(CR3R4)m-; m is 0, 1, or 2; R3 and R4 are hydrogen; and G4 is phenyl; wherein said salt is selected from the group consisting of sodium, potassium, magnesium, calcium, and tosylate exemplified by 4-[cis-2,6-dimethyl-4-(4- trifluoromethoxy-phenyl)-piperazine-1-sulfonyl]-indan-2-carboxylic acid for treating obesity, diabetes, hyperinsulinemia, metabolic syndrome X, dyslipidemia, or hypercholesterolemia; treating cardiovascular disease; treating inflammatory disease; or autoimmune disease rheumatoid arthritis, asthma, osteoarthritis, oxidative stress. |