| abstract |
Disclosed are peptide analogues of a-melanocyte-stimulating hormone (a-MSH), which posses an increased efficacy compared to the native a-MSH peptide. The a-MSH analogues exhibit increased anti-inflammatory effects and increased capability to prevent ischemic conditions compared to a-MSH. Further disclosed is the use of the peptides for the manufacture of pharmaceutical compositions for the treatment or prophylaxis of a condition in the tissue of one or more organs of a mammal, and moreover pharmaceutical compositions. |