| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b6042509de7544921c96de43b9da1438 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-715
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-665
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7052
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-702
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-26 |
| filingDate |
2005-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f90b8d3a9feff97a5490f7b69c5d959
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_706353c8a86b671868b9196a3a34ba4d |
| publicationDate |
2009-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
NZ-555739-A |
| titleOfInvention |
Antithrombotic dual inhibitors comprising a biotin residue |
| abstract |
Disclosed is an antithrombotic compound which has the general formula: oligosaccharide-spacer-A; wherein the oligosaccharide is a pentasaccharide residue of the formula (II); wherein R5 is a sulphonic acid residue or (1-8C)alkoxy, the charge being compensated by positively charged counterions; the spacer is an essentially pharmacologically inactive flexible linking residue having a chain length of 10 to 70 atoms, and further comprises at least one covalent bond with a biotin residue; and A is the residue -CH[NH-SO2-R1][CO-NR2-CH(4-benzamidine)-CO-NR3R4], wherein the remaining substituents are defined herein. Also disclosed is a pharmaceutical composition comprising a compound as defined above and pharmaceutically suitable auxiliaries. The use of the above compounds for the manufacture of a medicament for treating or preventing thrombosis or other thrombin-related diseases is further disclosed. |
| priorityDate |
2004-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |