abstract |
Provided is a composition comprising bacteria, wherein said bacteria consist of non-denatured killed Mycobacterium sp. containing less than 1.5 % of water, with the proviso that said composition does not comprise freeze-dried killed M. bovis BCG containing 1 to 2 % of water, dextran, sodium glutamate and glucose, obtained by freeze-drying of 1 g dry weight per litre of living Mycobacterium sp. suspended in an aqueous solution of 50 g/L dextran, 50 g/L sodium glutamate and 50 g/L glucose, until the water content is 1 % to 2 % by weight, and wherein said composition is able to induce a modulation of the immune response against a self-antigen or an allergen and does not induce inflammatory adverse effects by subcutaneous injection. (62) Divided Out of 533422 |