http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-554427-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_807fef65efe80114423da893a2c16c37 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 |
| filingDate | 2005-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efc6f86b6a0e6d72913b31d433a134a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9cd75891ae3d0104d5eae960542d65f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7dca9554ea7359d280b6aeebf8789810 |
| publicationDate | 2010-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-554427-A |
| titleOfInvention | Compositions and methods for inducing melanogenesis in a subject utilising afamelanotide |
| abstract | Disclosed is a topical composition for the transdermal delivery of an active agent, wherein the active agent is [Nle4, D-Phe7]-alpha-MSH (afamelanotide), wherein the composition is administered at a level not exceeding 10ng/ml in the plasma of the subject for a period of at least 4 hours, and wherein the composition comprises: (A) at least one solvent in which the active agent is soluble or which is modified to solubilise the active agent, and which has substantially the same dipole moment as that of the combination of active agent plus solvent system (such as lower aliphatic mono- and poly-hydroxy compounds); (B) at least one solvent modifier selected from the group consisting of terpene compounds (such as limonene, lemon oil, or a mixture of limonene and lemon oil); (C) methylsulfonylmethane; (D) an extract of Coleus forskolii; and, optionally, (E) at least one skin stabiliser for stimulating the body's repair mechanisms in response to transdermal migration of the active agent through the skin. Also disclosed is the use the above composition, in the manufacture of a topical preparation for inducing melanogenesis in a subject. Further disclosed is the use of a composition as defined above, in the manufacture of a topical preparation for preventing UV radiation-induced skin damage in a subject. |
| priorityDate | 2004-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 157.