abstract |
Disclosed is an indole derivative of formula (I), or an acid addition salt , hydrate, solvate thereof, wherein the substituents are as defined in the specification. Also disclosed is a process for preparing the above compound, and the use of the compound to treat pathologies which involve receptors of TRPV1, such as pain, inflammation, urological disorders, gynaecological disorders, gastrointestinal disorders, respiratory disorders, psoriasis, pruritus, irritation of the skin, eyes, or mucous membranes, herpes, shingles, or depression. |