http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-552898-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1224e3c07b7cc5684ee81d9e1e5ee15c |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N24-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B60-00 |
| filingDate | 2005-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76f7921e42522d26f5934de3f4c5a763 |
| publicationDate | 2011-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-552898-A |
| titleOfInvention | Method of producing a composition, composition and its use |
| abstract | The disclosure relates to a method for producing a liquid composition comprising hyperpolarised 13C-pyruvate said method comprising: (a) forming a liquid mixture comprising a radical of formula (I), 13C-pyruvic acid and/or 13C-pyruvate and freezing the mixture; (b) enhancing the 13C nuclear polarisation of pyruvic acid and/or pyruvate in the mixture via DNP; (c) adding a buffer and a base to the frozen mixture to dissolve it and to convert the 13C-pyruvic acid into a 13C-pyruvate to obtain a liquid composition or, when only 13C-pyruvate is used in step (a), adding a buffer to the frozen mixture to dissolve it to obtain a liquid composition; and (d) optionally removing the radical and/or reaction products thereof from the liquid composition. The comprising hyperpolarised 13C-pyruvate composition produced by this method is suitable for use as an imaging agent for in vivo MR imaging of a human or non-human animal body. |
| priorityDate | 2004-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 94.