| abstract |
Tetrahydroisoquinoline sulfonamide derivative compounds of formula (I) are disclosed, wherein the variables are as defined in the specification. These compounds are suitable for the treatment of obesity or diabetes or central nervous system disease or disorder such as vigilance or sleep disorder, narcolepsy, Alzheimer's disease or other dementias, Parkinson's disease, an attention disorder in hyperkinetic children, memory or learning disorder, epilepsy, schizophrenia, moderate cognitive disorders, depression, anxiety, sexual dysfunction, dizziness or travel sickness. |