| abstract |
Disclosed are compounds of formula (I) and processes for preparing them in free or salt form, wherein: Q is a bond; R1 and R2 are, independently, H or C1-C8alkyl; R3 is C1-C8alkyl; R4 and R5 are, independently, halogen, C1-C8alkyl, C1-C8-haloalkyl, a C3-C15- carbocyclic group, nitro, cyano, C1-C8-alkylsulfonyl, C1-C8-alkoxycarbonyl, C1-C8-alkoxy or C1-C8-haloalkoxy; R6 is H or C1-C8-alkyl; W is a mono or bicyclic ring as defined in the specification; X is -SO2-, -CH2-, -CH(C1-C8-alkyl)-, -CON(C1-C8-alkyl)- or a bond; m and n are each, independently, an integer from 0-3; and p is 1. Compounds of the invention are useful for the treatment of diseases mediated by the CRTh2 receptor, in particular inflammatory and allergic conditions. |