| abstract |
Disclosed are progesterone receptor modulating steroids of formula (I) which have both agonistic and antagonistic modulating activities towards the progesterone receptor, processes for their preparation, and their use in therapy, wherein the variables shown in formula (I) are as defined in the specification. These compounds of formula (I) are suitable for the treatment of endometriosis, for hormone replacement therapy or for the treatment of a gynaecological disorder, and as a contraceptive. |