http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-548685-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_56648a3835729246a809b1a3e2fd8117 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-102 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 |
filingDate | 2005-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03f829cc5fe957435a5bf01df0dbf4e6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a9a1febf9bc7a942d88bbffe679cd24 |
publicationDate | 2010-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | NZ-548685-A |
titleOfInvention | Reduction of spontaneous mutation rates in cells |
abstract | Provided is a process for making a cell having a reduced spontaneous mutation frequency comprising; a) introducing an antimutator allele of a gene encoding DNA polymerase IV and an antimutator allele of a gene encoding a sub-unit of DNA polymerase III; or b) introducing an antimutator allele of a gene encoding DNA polymerase IV or an antimutator allele of a gene encoding a sub-unit of DNA polymerase III, and overexpressing Mutl or MutS; or c) introducing an antimutator allele of a gene encoding DNA polymerase IV and an antimutator allele of a gene encoding a sub-unit of DNA polymerase III, and overexpressing Mutl or MutS; or d) introducing an antimutator allele of a gene encoding DNA polymerase IV and an antimutator allele of a gene encoding a sub-unit of DNA polymerase III, 15 and over-expressing Mutl and MutS. Further provided are cells obtained by the said process and use of such cells for the production of proteins and fermentation products. |
priorityDate | 2004-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 596.