| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24e76490bed88751680a5fef9bc73892 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate |
2004-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_462fd0acd11a7ae780460eeaec4ffff6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_102ac35931c3ba11e3e176d28f3d0bde
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb54c80355b2505f72019786ff33d94c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4acba840230dbd432d0eec450bf3c225
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d75a6926776367f67f610bf7cd4e28a0 |
| publicationDate |
2009-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
NZ-547471-A |
| titleOfInvention |
Process for the preparation of tubulin inhibitors |
| abstract |
Disclosed is a process for the preparation of 6-[(substituted) phenyl]-triazolopyrimidine dicarboxylic acid salt and as a hydrated salt having the structural formula (I) wherein: R1 is CF3 or C2F5; R2 is H or C1-C3 alkyl; n is an integer of 2, 3, or 4; X is Cl or Br; R3 and R4 are each independently H or C,-C3 alkyl; or R3 and R4 when optionally taken together with the nitrogen atom to which each is attached form a 4 to 6 membered saturated heterocyclic ring having 1-2 nitrogen atoms and 0-1 oxygen atoms or 0-1 sulphur atoms, and optionally substituted with R5; R5 is C,-C3 alkyl; wherein the dotted line is an optional bond. |
| priorityDate |
2003-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |