| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d8c72929deb0d5e6041dd021d8ab6e90 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-501
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5047 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1652
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1617
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1623
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-216
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5078
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1676 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-216
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 |
| filingDate |
2004-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0dd7a4968b9ba9f2dd706fe4c7820564
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fed3d39d069dc0e4e89eae6fd016cfbe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be5c66d8df061ee840c5731517034ae9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e5b3c3f67dcce0c555d108516e6269d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a12a5a031e52e348e379c728a7376814
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05f2b87ff96e7a33eb020fa76f5af3e0 |
| publicationDate |
2010-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
NZ-546692-A |
| titleOfInvention |
Pharmaceutical composition containing fenofibrate and method for the preparation thereof |
| abstract |
Disclosed is the use of a composition of fenofibrate containing micronized fenofibrate, a surfactant and a binding cellulose derivative as a solubilization adjuvant, said composition containing an amount of fenofibrate greater than or equal to 60% by weight for the preparation of a medicament for treating hypertriglyceridemias, hypercholesterolemias or hyperlipidemias while reducing the food effect on the bioavailability of fenofibrate, wherein said composition is in the form of granules comprising: (d) a neutral core; (e) an active layer, which surrounds the core; and (f) an outer layer; wherein said active layer comprises micronized fenofibrate, a surfactant and a binding cellulose derivative; and wherein said formulation has a dissolution profile of less than 10% at 5 minutes and more than 80% at 20 minutes according to the European Pharmacopoeia in a dissolution medium constituted by water with 0.025 M sodium lauryl sulphate. |
| priorityDate |
2003-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |