| abstract |
The use of (1) [lS[lR*,3R*(E),7R*,10S*,11R*,12R*,16S*]]-7-11-dihydroxy8,8,10,12, 16-pentamethyl-3-[1-methyl-2-(2-methyl-4thiazolyl)ethenyl]-4-aza-17 oxabicyclo [14.1.0] heptadecane-5,9-dione and (2) N(2-chloro-6-methylphenyl)-2-[[6-[4-(2hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide or pharmaceutically acceptable salt thereof, in the preparation of a medicament for sequential or simultaneous administration of (1) and (2) for synergistic treatment of a cancer selected from prostate cancer or breast cancer. |