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filingDate 2004-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4912258b2b1fbd40489f8dc502389a6a
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publicationDate 2008-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber NZ-544066-A
titleOfInvention New cytotoxic depsipeptides
abstract Disclosed is a compound of general formula (I) wherein R1 are each independently selected from the group consisting of hydrogen, halogen, cyano, hydroxyl, nitro, azido, substituted or unsubstituted alkyl, substituted or unsubstituted alkyldiene, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted alkoxy, substituted or unsubstituted aryl, substituted or unsubstituted heterocyclic group and substituted or unsubstituted acyl; R3 groups are independently selected from the group consisting of hydrogen, halogen, cyano, hydroxyl, nitro, azido, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted alkoxy, substituted or unsubstituted aryl, substituted or unsubstituted heterocyclic group and substituted or unsubstituted acyl; R4 groups are each independently selected from NR2, O and S; and R2 groups are each independently selected from the group consisting of hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted aryl, substituted or unsubstituted alkoxy and substituted or unsubstituted acyl, or a pharmaceutically acceptable salt or stereoisomer thereof. Also disclosed is the use of the above compound, or a pharmaceutically acceptable salt or stereoisomer thereof, in the preparation of a medicament for the treatment of cancer.
priorityDate 2003-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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