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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C317-28
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filingDate 2004-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dba7910008378f88d0fb7e53925d9e6a
publicationDate 2009-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber NZ-543237-A
titleOfInvention Process for the synthesis and/or preparation of modafinil having a defined granulometry
abstract Disclosed is a process for preparing modafinil having a granulometry wherein the ratio of median to mean is of 1:3 to 1:0.3 and median to mode is of 1:3 to 1:0.3, and having a granulometric median of between 2 and 60 micrometers, which comprises the steps of: (a) preparing a solution of DMSAM in a solvent, in which the concentration of DMSAM is of between 1 and 1.25 mol L-1; (b) contacting the solution obtained with NH3 at a temperature of between 15 Deg C and 65 Deg C and under a predetermined stirring; and (c) isolating the modafinil formed, wherein the stirring speed is predetermined in order to obtain said defined granulometry and granulometric median.
priorityDate 2003-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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