| abstract |
Disclosed is the use of a compound of formula (I) or a pharmaceutically acceptable salt thereof in the manufacture of a medicament for the treatment of psychosis, memory deficit, attention deficit disorder, migraine, neuropathy, neuro-inflammatory disorders, cerebral vascular injuries, head trauma, depression, stress, Huntingdon's disease, Tourette's syndrome, ischaemia, Parkinson's disease, schizophrenia, smoking cessation, treatment of nicotine dependence and/or treatment of symptoms of nicotine withdrawal, gastrointestinal disorders, eating disorders associated with excessive food intake, and non-insulin dependant diabetes mellitus, wherein R1 and R2 are independently selected from substituted or unsubstituted aryl; and R3 is hydrogen or substituted or unsubstituted alkyl; wherein at least one of R1 and R2 has a non-hydrogen substituent in the ortho-position(s) thereof relative to the point of attachment to the [-CH-O-] group. |