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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70
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filingDate 2004-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88c82ab6e629957c2996740a11e9305f
publicationDate 2008-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber NZ-541576-A
titleOfInvention Transdermal therapeutic system suitable for heat application for promoting the permeation of active substances, and the use thereof
abstract Disclosed is a transdermal therapeutic system (TTS) for a temporarily raised release rate of at least one pharmacological active substance by heating the TTS to a temperature between the skin temperature and 50°C inclusive and allowing the TTS to cool down after a certain time to skin temperature, comprising at least one backing layer impermeable to active substance, at least one matrix layer based on at least one polysiloxane including the abovementioned pharmacological active substance or substances, a detachable protective layer, and an internal and/or external heating element, where (a) the active substance-containing layer comprises, not taking the active substance into account, at least 80% by weight of a polysiloxane, (b) not more than 20% by weight of active substance is present in dissolved form, and (c) the active substance has a saturation solubility of 5% by weight in this polysiloxane.
priorityDate 2003-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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