| abstract |
The disclosure relates to a compound of the formula (I) or a pharmaceutically acceptable salt or solvate thereof, wherein the various moieties are as defined in the specification. The disclosure also provides pharmaceutical compositions containing the compound of the formula (I), and methods of treatment using these compounds. The disclosure also relates to the use of a combination of these compounds and one or more antiviral or other agents useful in the treatment of Human Immunodeficiency Virus (HIV). The disclosure further relates to the use of a compound of the formula (I), alone or in combination with another agent, in the treatment of solid organ transplant rejection, graft v. host disease, arthritis, rheumatoid arthritis, inflammatory bowel disease, atopic dermatitis, psoriasis, asthma, allergies or multiple sclerosis. |