| abstract |
Disclosed in a nitrooxyderivative or salt thereof having the following general formula (I) R-NR1c-(K)k0-(B)b0-(C)c0-NO2 (I) Wherein c0 is 1, b0 is 0, k0 is 0 or 1, R is the radical of a drug selected from lamotrigine, topiramate, zonisamide, carbamazepine, felbamate, amineptine, amoxapine, demexiptiline, desipramine, nortriptyline and tianeptine; or R is the radical of an analgestic drug having formula (II), wherein the rest of the substituents are defined in the specification. Also disclosed is the use of the above compound of formula (I) for the manufacture of a medicament for treating chronic pain. |