| abstract |
Disclosed are compounds of formula I wherein the substituents are as defined in the specification. Also disclosed is the use of compounds of formula I in the manufacture of medicaments for increasing levels of endogenous growth hormone in a patient in need thereof, for example for the treating or delaying HIV wasting syndrome, muscular atrophy, lipodistrophy, long term critical illness, osteoporosis, sarcopenia, frailty or ARFD in the elderly, obesity, renal disease, anorexia, sleep disorders, depression, Syndrome X, diabetes, congestive heart failure, cardiac myopathy, cardiac dysfunction associated with valvular disease and cachexia |