http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-537868-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J33-002 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 |
| filingDate | 2003-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f96f51b5214f8089f8961d580d6cb2b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65ced56081f25055d8cdd1e6fe2841b9 |
| publicationDate | 2006-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-537868-A |
| titleOfInvention | Polymorphis of a known thiophenecarboxylic acid dodecahydrocyclopenta (a) phenanthrenyl ester |
| abstract | Polymorphic crystal forms of 3-methylthiophene-2-carboxylic acid (6S,9R,10S,11S,13S,16R,17R)-9-chloro-6-fluoro-11-hydroxy-l7-methoxycarbonyl-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-l7-yl ester of formula (I) are disclosed. The crystal forms possess anti-inflammatory activity and have very good stability. Methods for preparing the crystal forms are also described. Particularly disclosed is a compound of formula (I) in a crystal form B that has a melting point, by Differential Scanning Calorimetry, of about 270 deg. C with simultaneous decomposition, at a heating rate of 20 deg. C/min and the diffraction lines (2theta in angular degrees ± 0.2 deg.) in the X-ray diffraction pattern as defined in the specification. |
| priorityDate | 2002-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 76.