| abstract |
Disclosed are caspase inhibitor of formula I and methods of preparing them wherein: X is CH; Y is halo, trifluorophenoxy, or tetrafluorophenoxy; R2 is ethyl, n-propyl or isopropyl; R3 is H, halo, OCF3, CH, or CF3; and R4 is H, halo, OCF3, SR, CH, CF3, Ar or T-Ar wherein R, Ar and T are as defined in the specification. Compounds of the type disclosed are useful in the preparation of medicaments for treating diseases where caspase activity is indicated. |