| abstract |
Use of [6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine-5-yl]-acetic acid of the formula (la), a physiologically acceptable salt or a physiologically hydrolysable ester thereof, in the preparation of a pharmaceutical composition for inhibiting a gastric proton pump, for reducing the sensitivity of gastric mucosa to topical injury or for treating or preventing gastric acid-related conditions is disclosed. These pharmaceutical compositions comprising the compound of formula (la) are suitable for treating or preventing gastric mucosal lesions, erosive gastritis, non-erosive gastritis, gastric ulceration, Ulcus duodeni or Ulcus ventriculi. |