| abstract |
Described are methods of identifying modulators of angiogenesis comprising: culturing a plurality of non-totipotent stem cells in the presence of a test compound, for a time and under conditions suitable for the growth of endothelial cells; and comparing the amount of microvessel outgrowth from the stem cells in the presence of the test compound as compared to a control of the amount of microvessel outgrowth. If the microvessel outgrowth is greater or less than the control level of microvessel outgrowth, the test compound is identified as a modulator of angiogenesis. |