| abstract |
A compound of Formula (IA) is disclosed, and its tautomers, prodrugs, solvates, or salts. R1 is an aryl or heteroaryl group, each optionally independently substituted with one to three substituent groups; R2 and R3 are each independently hydrogen or C1-C5 alkyl, or R2 and R3 together with the carbon atom they are commonly attached to form a C3-C8 spiro cycloalkyl ring; R4 is C1-C5 alkyl, C2-C5 alkenyl, or C2-C5 alkynyl, each optionally independently substituted with one to three substituent groups; R5 is a heteroaryl group optionally independently substituted with one to three substituent groups. The compound described is to be used to treat a disease sate or condition mediated by the glucocorticoid receptor function in a non-human patient. The disease state is selected from a group which includes obesity, neurological diseases, and cardiovascular diseases. |