http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-535261-A

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filingDate 2001-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc3407d31c5238e4780f511f449fc463
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publicationDate 2004-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber NZ-535261-A
titleOfInvention A tablet comprising the hydrochloride salt of N-(1-nbutyl-4-piperidinyl)methyl]-3,4-[1,3]oxazino[3,2-a] indole-10-carboxamide
abstract A pharmaceutical composition in the form of a tablet comprising the hydrochloride salt of N-[(1-nbutyl-4-piperidinyl) methyl]-3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxamide (SB207266) in combination with a pharmaceutically acceptable solid carrier and a process for manufacturing these tablets is disclosed. Use of a 5-HT4 receptor antagonist in the manufacture of a medicament for the prophylaxis or treatment of atrial arrhythmia in a mammal is also described. Use of SB 207266 or a pharmaceutically acceptable salt thereof in the manufacture of a medicament for the treatment or prophylaxis of atrial fibrillation in a mammal by administering to the mammal a daily oral or parenteral dosage regimen of about 0.2 mg to 1.0 mg of the SB 207266 or salt thereof per kg of total body weight (measured as the free base) is also disclosed. Particularly described is the use of SB 207266 or a pharmaceutically acceptable salt thereof in the prophylaxis or treatment of atrial arrhythmia in a mammal by administration of the SB 207266 or salt thereof on the first day at a loading dose of about 1.2 to about 2.0 times the daily maintenance dose, followed by administration of the SB 207266 or salt at the daily maintenance dose on subsequent days. (62) Divided out of 524108
priorityDate 2000-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Incoming Links

Predicate Subject
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Total number of triples: 41.