Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba92ba0a923a19b200b4fa2ac80370e1 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2009 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1611 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5383 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
filingDate |
2001-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc3407d31c5238e4780f511f449fc463 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99437b357cdcfefb2b05c22dead57a8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6efde4aaca614ac5d062b42b8abee442 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f402f4b38dfbaa4cd2173245cac0c1b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2155b6dff0186d230c114ded127a77c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d0835d09ee278c752d476f6727e3fcf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e20a0a7d592f7e5ad90f3c98735a2ebb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8355aa7c4f321f6988b740e4be562e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba6ebaeeb49387075d3328db11e9220d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbe4efd9ac7b7d39e4fc082ccd95b461 |
publicationDate |
2004-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
NZ-535261-A |
titleOfInvention |
A tablet comprising the hydrochloride salt of N-(1-nbutyl-4-piperidinyl)methyl]-3,4-[1,3]oxazino[3,2-a] indole-10-carboxamide |
abstract |
A pharmaceutical composition in the form of a tablet comprising the hydrochloride salt of N-[(1-nbutyl-4-piperidinyl) methyl]-3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxamide (SB207266) in combination with a pharmaceutically acceptable solid carrier and a process for manufacturing these tablets is disclosed. Use of a 5-HT4 receptor antagonist in the manufacture of a medicament for the prophylaxis or treatment of atrial arrhythmia in a mammal is also described. Use of SB 207266 or a pharmaceutically acceptable salt thereof in the manufacture of a medicament for the treatment or prophylaxis of atrial fibrillation in a mammal by administering to the mammal a daily oral or parenteral dosage regimen of about 0.2 mg to 1.0 mg of the SB 207266 or salt thereof per kg of total body weight (measured as the free base) is also disclosed. Particularly described is the use of SB 207266 or a pharmaceutically acceptable salt thereof in the prophylaxis or treatment of atrial arrhythmia in a mammal by administration of the SB 207266 or salt thereof on the first day at a loading dose of about 1.2 to about 2.0 times the daily maintenance dose, followed by administration of the SB 207266 or salt at the daily maintenance dose on subsequent days. (62) Divided out of 524108 |
priorityDate |
2000-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |