| abstract |
Use of an inhibitor or antagonist against tissue factor, TF, is described to be for the treatment or prevention of diabetes or diabetes related diseases. The inhibitor or antagonist binds to or enters insulin-producing cells and inhibits production and/or release of TF from the cells. The inhibitor or antagonist is an agent which completely or partially inhibits TF productions, such as an antibody or an antisense construct acting on the TF gene including L-arginin, pyrithione, pentoxifylline and cyclosporine A. |