abstract |
Disclosed is an orally administrable pharmaceutical dosage form for treating a patient at elevated cardiovascular risk, comprising a combination of: (a) a therapeutically effective daily dosage of a cholesterol-lowering agent, as a first active agent, (b) a therapeutically effective daily dosage of an inhibitor of the rennin-angiotensin system, as a second active agent, and (c) a therapeutically effective daily dosage of aspirin, as a third active agent, wherein at least one of the active agents is present in a dosage unit that physically separates the at least one active agent from the other active agents, and wherein the effective daily dosage units of each of the active agents of the combination have different release profiles. |