http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-531445-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5b459ec3f5254c20ccd5ca24931c4610 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J23-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2002-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2d4826464ec3e0bf76fb997f4cceb51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4492de41fa9c506df59050d279ea3b8 |
| publicationDate | 2004-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-531445-A |
| titleOfInvention | Three-step conversion of protected taxane ester to paclitaxel |
| abstract | A method of producing paclitaxel from a protected coupled ester compound of formula (I) is disclosed, wherein P1 is a hydrogenatable protecting group, comprising the steps of (a) deprotecting the 7-O-position and 3'-N-position of the protected coupled ester compound to form a first intermediate compound of formula (II); (b) benzoylating the first intermediate compound at the 3'-N-position thereby to form a second intermediate compound of formula (III); and (c) deprotecting the second intermediate compound by replacing P1 with hydrogen in the presence of an acid. Also disclosed are chemical compounds that are useful in the production of paclitaxel. |
| priorityDate | 2001-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.