| abstract |
A compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein Het is a 4-, 5-, or 6-membered aromatic or alifatic heterocyclic group containing at least one nitrogen, oxygen or sulphur atom, substituted with a R3 and a R4 group in the ortho positions; R1 is H, CH3, or CH2OH; R2 is CH3 or CH2CH3; R3, and R4 are independently selected from the group of H, C1-C6 alkyl, hydroxylated C1-C6 alkyl, or halogen; R5 and R6 are independently selected substituents, comprising C, H, N, O, S Se, P and halogen atoms, which give compounds of Formula I a molecular weight less than or equal to 600; R5 and R6 may together with the nitrogen atom to which they are attached form a saturated or unsaturated ring optionally containing one or more further heteroatoms; and X is NH, or O. |